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Anti-Mouse ADGRB1/BAI1 Polyclonal Antibody

  • Cat. No.:RB9TMT218014
  • Price:Negotiable
  • Clicks:203

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityRat, Mouse, Human
TargetAdgrb1, Adhesion G protein-coupled receptor B1, Bai1, Brain-specific angiogenesis inhibitor 1, Vasculostatin-120, Vasculostatin-40, Vstat-40, Vstat120
ImmunogenE. coli - derived recombinant Mouse ADGRB1/BAI1 (Ser636-Thr940).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ3UHD1
Background

Adhesion G protein-coupled receptor B1 (ADGRB1/BAI1) is a ~173 kDa protein. Phosphatidylserine receptor which enhances the engulfment of apoptotic cells. Also mediates the binding and engulfment of Gram-negative bacteria. Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity. In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells. Promotes myoblast fusion.

1. Park, D. et al. (2007) Nature 450, 430-4. PMID: 17960134
2. Das, S. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 2136-41. PMID: 21245295
3. Billings, EA. et al. (2016) Science signaling 9, ra14. PMID: 26838550
4. Hochreiter-Hufford, AE. et al. (2013) Nature 497, 263-7. PMID: 23615608
5. Zhu, D. et al. (2015) The Journal of clinical investigation 125, 1497-508. PMID: 25751059
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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