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Anti-MeV Nucleoprotein Polyclonal Antibody

  • Cat. No.:RB9TVK397014
  • Price:Negotiable
  • Clicks:468

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMeasles virus
TargetN, NP, Nucleocapsid protein, Nucleoprotein, Protein N
ImmunogenE. coli - derived recombinant MeV Nucleoprotein (Thr21-Arg408).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ77M43
Background

Nucleoprotein is a ~58 kDa protein. Forms the helical nucleocapsid (NC) in a ratio of 1 N per 6 ribonucleotides, protecting the genome from nucleases. The nucleocapsid (NC) has a helical structure with either 12.35 or 11.64 N per turn, approximately 20 nm in diameter, with a hollow central cavity approximately 5 nm in diameter. The encapsidated genomic RNA serves as template for transcription and replication; encapsidation by N is coupled to RNA synthesis. Forms the encapsidation complex with the phosphoprotein protein P. Before encapsidation, the newly synthesized free N protein, so-called N0, is chaperoned by P.

1. Desfosses, A. et al. (2019) Proceedings of the National Academy of Sciences of the United States of America 116, 4256-4264. PMID: 30787192
2. Zhou, Y. et al. (2019) Journal of virology 93. PMID: 31375591
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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