Anti-Human SSB Polyclonal Antibody
- Cat. No.：RB9THY125014
- Price：Negotiable
- Clicks：471
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse, Rat |
| Target | La autoantigen, La ribonucleoprotein, Lupus La protein, SS-B, SSB, Sjoegren syndrome type B antigen |
| Immunogen | E. coli - derived recombinant Human SSB (Ala2-Lys185). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P05455 |
| Background | Lupus La protein (SSB) is a ~46 kDa protein. Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation. In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation. 1. Gottlieb, E. et al. (1989) The EMBO journal 8, 851-61. PMID: 2470590 2. Chambers, JC. et al. (1988) The Journal of biological chemistry 263, 18043-51. PMID: 3192525 3. Ray, PS. et al. (2002) Nucleic acids research 30, 4500-8. PMID: 12384597 |
| Note | For research use only |
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