Anti-Human ING5 Polyclonal Antibody
- Cat. No.：RB9THD420014
- Price：Negotiable
- Clicks：443
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse |
| Target | ING5, Inhibitor of growth protein 5, p28ING5 |
| Immunogen | E. coli - derived recombinant Human ING5 (Ala2-Ala105). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q8WYH8 |
| Background | Inhibitor of growth protein 5 (ING5) is a ~27 kDa protein. Component of the HBO1 complex, which specifically mediates acetylation of histone H3 at 'Lys-14' (H3K14ac) and, to a lower extent, acetylation of histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator. Inhibits cell growth, induces a delay in S-phase progression and enhances Fas-induced apoptosis in an INCA1-dependent manner. 1. Lalonde, ME. et al. (2013) Genes & development 27, 2009-24. PMID: 24065767 2. Doyon, Y. et al. (2006) Molecular cell 21, 51-64. PMID: 16387653 3. Shiseki, M. et al. (2003) Cancer research 63, 2373-8. PMID: 12750254 4. Zhang, F. et al. (2011) PloS one 6, e21505. PMID: 21750715 |
| Note | For research use only |
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