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Anti-Human F7 Polyclonal Antibody

  • Cat. No.:RB9THY060024
  • Price:Negotiable
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Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman
TargetCoagulation factor VII, EC:3.4.21.21, Eptacog alfa, F7, Factor VII heavy chain, Factor VII light chain, Proconvertin, SPCA, Serum prothrombin conversion accelerator
ImmunogenE. coli - derived recombinant Human F7 (Ile213-Pro466).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP08709
Background

Coagulation factor VII (F7) is a ~51 kDa protein. Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa also converts factor IX to factor IXa in the presence of tissue factor and calcium.

1. Osterud, B. et al. (1977) Proceedings of the National Academy of Sciences of the United States of America 74, 5260-4. PMID: 271951
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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