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Anti-Human CD265/TNFRSF11A Polyclonal Antibody

  • Cat. No.:RB9THV008014
  • Price:Negotiable
  • Clicks:177

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman
TargetCD265, ODFR, Osteoclast differentiation factor receptor, RANK, Receptor activator of NF-KB, TNFRSF11A, Tumor necrosis factor receptor superfamily member 11A
ImmunogenE. coli - derived recombinant Human CD265/TNFRSF11A (Ser36-Ser195).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ9Y6Q6
Background

Tumor necrosis factor receptor superfamily member 11A (CD265/TNFRSF11A) is a ~66 kDa protein. Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2. Involved in the regulation of interactions between T-cells and dendritic cells.

1. Nakagawa, N. et al. (1998) Biochemical and biophysical research communications 253, 395-400. PMID: 9878548
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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