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Anti-Human KL Polyclonal Antibody

  • Cat. No.:RB9THV160024
  • Price:Negotiable
  • Clicks:356

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Human
TargetEC:3.2.1.31, KL, Klotho, Klotho peptide
ImmunogenE. coli - derived recombinant Human KL (Glu34-Gly505).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ9UEF7
Background

Klotho is a ~116 kDa protein. May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1.

NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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