Anti-Human PAPPA Polyclonal Antibody
- Cat. No.：RB9THC474014
- Price：Negotiable
- Clicks：310
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | EC:3.4.24.79, IGF-dependent IGFBP-4 protease, IGFBP-4ase, Insulin-like growth factor-dependent IGF-binding protein 4 protease, PAPP-A, PAPPA, Pappalysin-1, Pregnancy-associated plasma protein A |
| Immunogen | E. coli - derived recombinant Human PAPPA (Leu317-Pro532). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q13219 |
| Background | Pappalysin-1 is a ~180 kDa protein. Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF. |
| Note | For research use only |
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