Anti-Human CCR4 Polyclonal Antibody
- Cat. No.：RB9THW634014
- Price：Negotiable
- Clicks：505
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Homo sapiens (Human) |
| Target | C-C CKR-4, C-C chemokine receptor type 4, CC-CKR-4, CCR-4, CCR4, CD194, CMKBR4, K5-5 |
| Immunogen | E. coli - derived recombinant Human CCR4 (Asn2-Glu39&Ser176-Ile206&Glu309-Leu360). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P51679 |
| Background | C-C chemokine receptor type 4 (CCR4) is a ~41 kDa protein. High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. |
| Note | For research use only |
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