Anti-Human CMKLR2 Polyclonal Antibody
- Cat. No.：RB9THD623014
- Price：Negotiable
- Clicks：318
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Homo sapiens (Human) |
| Target | CMKLR2, Chemerin chemokine-like receptor 2, Chemerin-like receptor 2, Chemokine-like receptor 2, G-protein coupled receptor 1, GPR1 |
| Immunogen | E. coli - derived recombinant Human CMKLR2 (Glu2-Ser41&Ser308-Gln355). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P46091 |
| Background | Chemerin-like receptor 2 (CMKLR2) is a ~41 kDa protein. Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis. Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates weakly G proteins, calcium mobilization and MAPK1/MAPK3 (ERK1/2) phosphorylation too. Also acts as a receptor for TAFA1, mediates its effects on neuronal stem-cell proliferation and differentiation via the activation of ROCK/ERK and ROCK/STAT3 signaling pathway. 1. Barnea, G. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 64-9. PMID: 18165312 2. De Henau, O. et al. (2016) PloS one 11, e0164179. PMID: 27716822 |
| Note | For research use only |
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