Anti-Human UGDH Polyclonal Antibody
- Cat. No.：RB9THA400014
- Price：Negotiable
- Clicks：545
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Rat, Mouse |
| Target | EC:1.1.1.22, UDP-Glc dehydrogenase, UDP-GlcDH, UDP-glucose 6-dehydrogenase, UDPGDH, UGDH |
| Immunogen | E. coli - derived recombinant Human UGDH (Met1-Val494). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | O60701 |
| Background | UDP-glucose 6-dehydrogenase (UGDH) is a ~55 kDa protein. Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans. Required for proper brain and neuronal development. 1. Egger, S. et al. (2011) The Journal of biological chemistry 286, 23877-87. PMID: 21502315 2. Sennett, NC. et al. (2011) Biochemistry 50, 9651-63. PMID: 21961565 3. Egger, S. et al. (2012) The Journal of biological chemistry 287, 2119-29. PMID: 22123821 4. Sennett, NC. et al. (2012) Biochemistry 51, 9364-74. PMID: 23106432 5. Kadirvelraj, R. et al. (2014) Biochemistry 53, 8043-51. PMID: 25478983 6. Beattie, NR. et al. (2017) Biochemistry 56, 202-211. PMID: 27966912 7. Keul, ND. et al. (2018) Nature 563, 584-588. PMID: 30420606 8. Beattie, NR. et al. (2018) Biochemistry 57, 6848-6859. PMID: 30457329 9. Hengel, H. et al. (2020) Nature communications 11, 595. PMID: 32001716 |
| Note | For research use only |
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