Anti-Human TNIK Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Human, Mouse
Target	EC:2.7.11.1, KIAA0551, TNIK, TRAF2 and NCK-interacting protein kinase
Immunogen	E. coli - derived recombinant Human TNIK (Met1-Asp291).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q9UKE5
Background	TRAF2 and NCK-interacting protein kinase (TNIK) is a ~154 kDa protein. Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. 1. Meng, Z. et al. (2015) Nature communications 6, 8357. PMID: 26437443
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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