Anti-Human TNIK Polyclonal Antibody
- Cat. No.：RB9THA247024
- Price：Negotiable
- Clicks：465
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse |
| Target | EC:2.7.11.1, KIAA0551, TNIK, TRAF2 and NCK-interacting protein kinase |
| Immunogen | E. coli - derived recombinant Human TNIK (Met1-Asp291). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9UKE5 |
| Background | TRAF2 and NCK-interacting protein kinase (TNIK) is a ~154 kDa protein. Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. 1. Meng, Z. et al. (2015) Nature communications 6, 8357. PMID: 26437443 |
| Note | For research use only |
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