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Anti-Human KLF10 Polyclonal Antibody

  • Cat. No.:RB9THC085014
  • Price:Negotiable
  • Clicks:583

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman, Mouse, Rat
TargetEGR-alpha, KLF10, Krueppel-like factor 10, TGFB-inducible early growth response protein 1, TIEG, TIEG-1, TIEG1, Transforming growth factor-beta-inducible early growth response protein 1
ImmunogenE. coli - derived recombinant Human KLF10 (Lys382-Gln480).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ13118
Background

Krueppel-like factor 10 (KLF10) is a ~52 kDa protein. Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis. May play a role in the cell cycle regulation.

NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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