| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Human |
| Target | CCDC85B, Coiled-coil domain-containing protein 85B, DIPA, Delta-interacting protein A, Hepatitis delta antigen-interacting protein A |
| Immunogen | E. coli - derived recombinant Human CCDC85B (Met1-Asp202). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q15834 |
| Background | Coiled-coil domain-containing protein 85B (CCDC85B) is a ~22 kDa protein. Functions as a transcriptional repressor. May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth. May function in adipocyte differentiation, negatively regulating mitotic clonal expansion. Plays a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family. 1. Du, X. et al. (2006) Experimental and molecular pathology 81, 184-90. PMID: 17014843 2. Iwai, A. et al. (2008) Oncogene 27, 1520-6. PMID: 17873903 |
| Note | For research use only |