Anti-Human SOX11 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Rat, Mouse, Human
Target	SOX11, Transcription factor SOX-11
Immunogen	E. coli - derived recombinant Human SOX11 (Asn54-Tyr113).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	P35716
Background	Transcription factor SOX-11 (SOX11) is a ~46 kDa protein. Transcription factor that acts as a transcriptional activator. Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation. Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron. Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis. 1. Tsurusaki, Y. et al. (2014) Nature communications 5, 4011. PMID: 24886874 2. Hempel, A. et al. (2016) Journal of medical genetics 53, 152-62. PMID: 26543203
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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