Anti-Human MMP24 Polyclonal Antibody
- Cat. No.：RB9THV667024
- Price：Negotiable
- Clicks：405
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Rat, Mouse, Human |
| Target | EC:3.4.24.-, MMP-24, MMP24, MT-MMP 5, MT5-MMP, MT5MMP, MTMMP5, Matrix metalloproteinase-24, Membrane-type matrix metalloproteinase 5, Membrane-type-5 matrix metalloproteinase, Processed matrix metallo |
| Immunogen | E. coli - derived recombinant Human MMP24 (Ile379-Trp566). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9Y5R2 |
| Background | Matrix metalloproteinase-24 (MMP24) is a ~73 kDa protein. Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence. Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by mediating cleavage of CDH2, thereby acting as a mediator of peripheral thermal nociception and inflammatory hyperalgesia. Key regulator of neural stem cells quiescence by mediating cleavage of CDH2, affecting CDH2-mediated anchorage of neural stem cells to ependymocytes in the adult subependymal zone, leading to modulate their quiescence. May play a role in axonal growth. Able to activate progelatinase A. |
| Note | For research use only |
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