Anti-Human AHI1 Polyclonal Antibody
- Cat. No.：RB9THV430014
- Price：Negotiable
- Clicks：315
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | AHI-1, AHI1, Abelson helper integration site 1 protein homolog, Jouberin |
| Immunogen | E. coli - derived recombinant Human AHI1 (Arg596-Ile917). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q8N157 |
| Background | Jouberin (AHI1) is a ~137 kDa protein. Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development. 1. Lancaster, MA. et al. (2011) Nature medicine 17, 726-31. PMID: 21623382 |
| Note | For research use only |
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