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Anti-Human KCNIP4 Polyclonal Antibody

  • Cat. No.:RB9THA290014
  • Price:Negotiable
  • Clicks:188

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityRat, Mouse, Human
TargetA-type potassium channel modulatory protein 4, CALP, Calsenilin-like protein, KCHIP4, KCNIP4, KChIP4, Kv channel-interacting protein 4, Potassium channel-interacting protein 4
ImmunogenE. coli - derived recombinant Human KCNIP4 (Ser56-Ile250).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ6PIL6
Background

Kv channel-interacting protein 4 (KCNIP4) is a ~28 kDa protein. Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Modulates KCND3/Kv4.3 currents. Isoform 4 does not increase KCND2 expression at the cell membrane. Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane.

1. Morohashi, Y. et al. (2002) The Journal of biological chemistry 277, 14965-75. PMID: 11847232
2. Jerng, HH. et al. (2008) The Journal of biological chemistry 283, 36046-59. PMID: 18957440
3. Tang, YQ. et al. (2013) The Journal of biological chemistry 288, 14727-41. PMID: 23576435
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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