Anti-Human DHX8/DDX8 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Mouse, Human
Target	ATP-dependent RNA helicase DHX8, DDX8, DEAH box protein 8, DHX8, EC:3.6.4.13, RNA helicase HRH1
Immunogen	E. coli - derived recombinant Human DHX8/DDX8 (Val917-Arg1220).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q14562
Background	ATP-dependent RNA helicase DHX8 (DDX8) is a ~139 kDa protein. Involved in pre-mRNA splicing as component of the spliceosome. Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. 1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638 2. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346 3. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770 4. Ohno, M. et al. (1996) Genes & development 10, 997-1007. PMID: 8608946
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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