| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Human |
| Target | ATP-dependent RNA helicase DHX8, DDX8, DEAH box protein 8, DHX8, EC:3.6.4.13, RNA helicase HRH1 |
| Immunogen | E. coli - derived recombinant Human DHX8/DDX8 (Val917-Arg1220). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q14562 |
| Background | ATP-dependent RNA helicase DHX8 (DDX8) is a ~139 kDa protein. Involved in pre-mRNA splicing as component of the spliceosome. Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. 1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638 2. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346 3. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770 4. Ohno, M. et al. (1996) Genes & development 10, 997-1007. PMID: 8608946 |
| Note | For research use only |