| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Rat, Mouse, Human |
| Target | ABP-280-like protein, ABP-L, ABPL, Actin-binding-like protein, FLN-C, FLN2, FLNC, FLNc, Filamin-2, Filamin-C, Gamma-filamin |
| Immunogen | E. coli - derived recombinant Human FLNC (Glu17-Lys259). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q14315 |
| Background | Filamin-C (FLNC) is a ~291 kDa protein. Muscle-specific filamin, which plays a central role in sarcomere assembly and organization. Critical for normal myogenesis, it probably functions as a large actin-cross-linking protein with structural functions at the Z lines in muscle cells. May be involved in reorganizing the actin cytoskeleton in response to signaling events. 1. Agarwal, R. et al. (2021) Circulation research 129, 751-766. PMID: 34405687 |
| Note | For research use only |