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Anti-Human FLNC Polyclonal Antibody

  • Cat. No.:RB9THC548014
  • Price:Negotiable
  • Clicks:509

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityRat, Mouse, Human
TargetABP-280-like protein, ABP-L, ABPL, Actin-binding-like protein, FLN-C, FLN2, FLNC, FLNc, Filamin-2, Filamin-C, Gamma-filamin
ImmunogenE. coli - derived recombinant Human FLNC (Glu17-Lys259).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ14315
Background

Filamin-C (FLNC) is a ~291 kDa protein. Muscle-specific filamin, which plays a central role in sarcomere assembly and organization. Critical for normal myogenesis, it probably functions as a large actin-cross-linking protein with structural functions at the Z lines in muscle cells. May be involved in reorganizing the actin cytoskeleton in response to signaling events.

1. Agarwal, R. et al. (2021) Circulation research 129, 751-766. PMID: 34405687
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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