| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, EC:2.5.1.1, EC:2.5.1.10, FDPS, FPP synthase, FPS, Farnesyl diphosphate synthase, Farnesyl pyrophosphate synthase, Geranyltranstran |
| Immunogen | E. coli - derived recombinant Human FDPS (Asp74-Lys419). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P14324 |
| Background | Farnesyl pyrophosphate synthase (FDPS) is a ~48 kDa protein. Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. |
| Note | For research use only |