| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | A-kinase anchor protein 18 kDa, A-kinase anchor protein 7 isoforms alpha and beta, AKAP 18, AKAP-7 isoforms alpha and beta, AKAP15, AKAP18, AKAP7, PRKA7 isoforms alpha/beta, Protein kinase A-anchoring |
| Immunogen | E. coli - derived recombinant Human AKAP7 (Met1-Lys104). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | O43687 |
| Background | A-kinase anchor protein 7 isoforms alpha and beta (AKAP7) is a ~11 kDa protein. Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. |
| Note | For research use only |