Anti-Human PRC1 Polyclonal Antibody
- Cat. No.：RB9THD582014
- Price：Negotiable
- Clicks：189
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | PRC1, Protein regulator of cytokinesis 1 |
| Immunogen | E. coli - derived recombinant Human PRC1 (Met1-Ser466). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | O43663 |
| Background | Protein regulator of cytokinesis 1 (PRC1) is a ~71 kDa protein. Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. 1. Kanehira, M. et al. (2007) Cancer research 67, 3276-85. PMID: 17409436 |
| Note | For research use only |
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