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Anti-Human RPA4 Polyclonal Antibody

  • Cat. No.:RB9THD580014
  • Price:Negotiable
  • Clicks:416

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman
TargetRF-A protein 4, RP-A p30, RPA4, Replication factor A protein 4, Replication protein A 30 kDa subunit
ImmunogenE. coli - derived recombinant Human RPA4 (Cys49-Asp261).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ13156
Background

Replication protein A 30 kDa subunit (RPA4) is a ~28 kDa protein. As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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