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Anti-Human SLC6A2 NAT1 NET1 SLC6A5 Polyclonal Antibody
- Cat. No.：RB9THD570014
- Price：Negotiable
- Clicks：301
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Homo sapiens (Human) |
| Target | NAT1, NET, NET1, Norepinephrine transporter, SLC6A2, SLC6A5, Sodium-dependent noradrenaline transporter, Solute carrier family 6 member 2 |
| Immunogen | E. coli - derived recombinant Human SLC6A2 NAT1 NET1 SLC6A5 (Phe167-Pro233&Ser363-Thr402&Pro570-Ile617). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P23975 |
| Background | Sodium-dependent noradrenaline transporter (SLC6A2 NAT1 NET1 SLC6A5) is a ~69 kDa protein. Mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline), the primary signaling neurotransmitter in the autonomic sympathetic nervous system. Is responsible for norepinephrine re-uptake and clearance from the synaptic cleft, thus playing a crucial role in norepinephrine inactivation and homeostasis. Can also mediate sodium- and chloride-dependent transport of dopamine. 1. Pacholczyk, T. et al. (1991) Nature 350, 350-4. PMID: 2008212 2. Gu, H. et al. (1994) The Journal of biological chemistry 269, 7124-30. PMID: 8125921 3. Zhang, H. et al. (2024) Nature 630, 247-254. PMID: 38750358 4. Syringas, M. et al. (2000) Molecular pharmacology 58, 1404-11. PMID: 11093780 5. Brown, CR. et al. (2025) Journal of neurochemistry 169, e16241. PMID: 39395208 6. Tan, J. et al. (2024) Nature 632, 921-929. PMID: 39048818 |
| Note | For research use only |
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