| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | EPO, Epoetin, Erythropoietin |
| Immunogen | E. coli - derived recombinant Human EPO (Ala28-Arg193). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P01588 |
| Background | Erythropoietin (EPO) is a ~21 kDa protein. Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. 1. Kim, AR. et al. (2017) Cell 168, 1053-1064.e15. PMID: 28283061 2. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108 |
| Note | For research use only |