Anti-Human ERP44 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Mouse, Human
Target	ER protein 44, ERP44, ERp44, Endoplasmic reticulum resident protein 44, KIAA0573, TXNDC4, Thioredoxin domain-containing protein 4
Immunogen	E. coli - derived recombinant Human ERP44 (Thr36-Leu406).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q9BS26
Background	Endoplasmic reticulum resident protein 44 (ERP44) is a ~46 kDa protein. Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum. 1. Anelli, T. et al. (2002) The EMBO journal 21, 835-44. PMID: 11847130 2. Anelli, T. et al. (2003) The EMBO journal 22, 5015-22. PMID: 14517240 3. Higo, T. et al. (2005) Cell 120, 85-98. PMID: 15652484 4. Zhang, J. et al. (2018) The EMBO journal 37. PMID: 29858230
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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