| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Human |
| Target | ER protein 44, ERP44, ERp44, Endoplasmic reticulum resident protein 44, KIAA0573, TXNDC4, Thioredoxin domain-containing protein 4 |
| Immunogen | E. coli - derived recombinant Human ERP44 (Thr36-Leu406). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9BS26 |
| Background | Endoplasmic reticulum resident protein 44 (ERP44) is a ~46 kDa protein. Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum. 1. Anelli, T. et al. (2002) The EMBO journal 21, 835-44. PMID: 11847130 2. Anelli, T. et al. (2003) The EMBO journal 22, 5015-22. PMID: 14517240 3. Higo, T. et al. (2005) Cell 120, 85-98. PMID: 15652484 4. Zhang, J. et al. (2018) The EMBO journal 37. PMID: 29858230 |
| Note | For research use only |