Anti-Human DNMBP Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Human
Target	ARHGEF36, DNMBP, Dynamin-binding protein, KIAA1010, Scaffold protein Tuba, TUBA
Immunogen	E. coli - derived recombinant Human DNMBP (Met1-Leu202).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q6XZF7
Background	Dynamin-binding protein (DNMBP) is a ~177 kDa protein. Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis. May play a role in membrane trafficking between the cell surface and the Golgi. 1. Otani, T. et al. (2006) The Journal of cell biology 175, 135-46. PMID: 17015620 2. Rajabian, T. et al. (2009) Nature cell biology 11, 1212-8. PMID: 19767742 3. Qin, Y. et al. (2010) The Journal of cell biology 189, 661-9. PMID: 20479467
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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