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Anti-Human DNMBP Polyclonal Antibody

  • Cat. No.:RB9THD555014
  • Price:Negotiable
  • Clicks:416

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman
TargetARHGEF36, DNMBP, Dynamin-binding protein, KIAA1010, Scaffold protein Tuba, TUBA
ImmunogenE. coli - derived recombinant Human DNMBP (Met1-Leu202).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ6XZF7
Background

Dynamin-binding protein (DNMBP) is a ~177 kDa protein. Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells. Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation. Plays a role in ciliogenesis. May play a role in membrane trafficking between the cell surface and the Golgi.

1. Otani, T. et al. (2006) The Journal of cell biology 175, 135-46. PMID: 17015620
2. Rajabian, T. et al. (2009) Nature cell biology 11, 1212-8. PMID: 19767742
3. Qin, Y. et al. (2010) The Journal of cell biology 189, 661-9. PMID: 20479467
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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