Anti-Human PLOD1 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Rat, Mouse, Human
Target	EC:1.14.11.4, LH1, LLH, Lysyl hydroxylase 1, PLOD, PLOD1, Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
Immunogen	E. coli - derived recombinant Human PLOD1 (Gln636-Pro727).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q02809
Background	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1) is a ~83 kDa protein. Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links (Probable). 1. Yeowell, HN. et al. (2000) Matrix biology : journal of the International Society for Matrix Biology 19, 37-46. PMID: 10686424 2. Walker, LC. et al. (2005) The Journal of investigative dermatology 124, 914-8. PMID: 15854030 3. Pirskanen, A. et al. (1996) The Journal of biological chemistry 271, 9398-402. PMID: 8621606
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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