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Anti-Human PLOD1 Polyclonal Antibody

  • Cat. No.:RB9THX220014
  • Price:Negotiable
  • Clicks:269

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityRat, Mouse, Human
TargetEC:1.14.11.4, LH1, LLH, Lysyl hydroxylase 1, PLOD, PLOD1, Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
ImmunogenE. coli - derived recombinant Human PLOD1 (Gln636-Pro727).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ02809
Background

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1) is a ~83 kDa protein. Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links (Probable).

1. Yeowell, HN. et al. (2000) Matrix biology : journal of the International Society for Matrix Biology 19, 37-46. PMID: 10686424
2. Walker, LC. et al. (2005) The Journal of investigative dermatology 124, 914-8. PMID: 15854030
3. Pirskanen, A. et al. (1996) The Journal of biological chemistry 271, 9398-402. PMID: 8621606
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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