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Anti-Human CDH23 Polyclonal Antibody

  • Cat. No.:RB9THP584014
  • Price:Negotiable
  • Clicks:472

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Rat, Human
TargetCDH23, Cadherin-23, KIAA1774, KIAA1812, Otocadherin
ImmunogenE. coli - derived recombinant Human CDH23 (His34-Phe236).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ9H251
Background

Cadherin-23 (CDH23) is a ~369 kDa protein. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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