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Anti-Human KHDRBS3 Polyclonal Antibody

  • Cat. No.:RB9THD548014
  • Price:Negotiable
  • Clicks:393

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityRat, Mouse, Human
TargetKH domain-containing, RNA-binding, signal transduction-associated protein 3, KHDRBS3, RNA-binding protein T-Star, SALP, SLM-2, SLM2, Sam68-like mammalian protein 2, Sam68-like phosphotyrosine protein
ImmunogenE. coli - derived recombinant Human KHDRBS3 (Asn51-Gly176).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberO75525
Background

KH domain-containing, RNA-binding, signal transduction-associated protein 3 (KHDRBS3) is a ~38 kDa protein. RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides. Binds poly(A). RNA-binding abilities are down-regulated by tyrosine kinase PTK6.

1. Lee, J. et al. (1999) Gene 240, 133-47. PMID: 10564820
2. Ray, D. et al. (2009) Nature biotechnology 27, 667-70. PMID: 19561594
3. Feracci, M. et al. (2016) Nature communications 7, 10355. PMID: 26758068
4. Cohen, CD. et al. (2005) Journal of the American Society of Nephrology : JASN 16, 1958-65. PMID: 15901763
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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