Anti-Human GALNT3 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Mouse, Human
Target	EC:2.4.1.41, GALNT3, GalNAc-T3, Polypeptide GalNAc transferase 3, Polypeptide N-acetylgalactosaminyltransferase 3, Protein-UDP acetylgalactosaminyltransferase 3, UDP-GalNAc:polypeptide N-acetylgalacto
Immunogen	E. coli - derived recombinant Human GALNT3 (Thr186-Asn555).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q14435
Background	Polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3) is a ~72 kDa protein. Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, MUC2, MUC1A and MUC5AC. Probably glycosylates fibronectin in vivo. Glycosylates FGF23. 1. Kato, K. et al. (2006) The Journal of biological chemistry 281, 18370-7. PMID: 16638743 2. de Las Rivas, M. et al. (2020) Nature chemical biology 16, 351-360. PMID: 31932717 3. Bennett, EP. et al. (1996) The Journal of biological chemistry 271, 17006-12. PMID: 8663203 4. Wandall, HH. et al. (1997) The Journal of biological chemistry 272, 23503-14. PMID: 9295285
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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