| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Human |
| Target | EC:2.4.1.41, GALNT3, GalNAc-T3, Polypeptide GalNAc transferase 3, Polypeptide N-acetylgalactosaminyltransferase 3, Protein-UDP acetylgalactosaminyltransferase 3, UDP-GalNAc:polypeptide N-acetylgalacto |
| Immunogen | E. coli - derived recombinant Human GALNT3 (Thr186-Asn555). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q14435 |
| Background | Polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3) is a ~72 kDa protein. Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, MUC2, MUC1A and MUC5AC. Probably glycosylates fibronectin in vivo. Glycosylates FGF23. 1. Kato, K. et al. (2006) The Journal of biological chemistry 281, 18370-7. PMID: 16638743 2. de Las Rivas, M. et al. (2020) Nature chemical biology 16, 351-360. PMID: 31932717 3. Bennett, EP. et al. (1996) The Journal of biological chemistry 271, 17006-12. PMID: 8663203 4. Wandall, HH. et al. (1997) The Journal of biological chemistry 272, 23503-14. PMID: 9295285 |
| Note | For research use only |