Anti-Human YJEFN3 Polyclonal Antibody
- Cat. No.：RB9THT044014
- Price：Negotiable
- Clicks：375
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | AIBP2, ApoA-I-binding protein 2, YJEFN3, YjeF N-terminal domain-containing protein 3, YjeF_N3, hYjeF_N3 |
| Immunogen | E. coli - derived recombinant Human YJEFN3 (Met1-Leu299). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | A6XGL0 |
| Background | YjeF N-terminal domain-containing protein 3 (YJEFN3) is a ~32 kDa protein. May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endothelium, a type of specialized endothelium manifesting hematopoietic potential. YJEFN3-mediated cholesterol efflux activates endothelial SREBF2, the master transcription factor for cholesterol biosynthesis, which in turn transactivates NOTCH and promotes hematopoietic stem and progenitor cell emergence. May play a role in spermiogenesis and oogenesis. 1. Rudolph, C. et al. (2007) Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 39, 322-35. PMID: 17533573 |
| Note | For research use only |
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