Anti-Human RIOK1 Polyclonal Antibody
- Cat. No.：RB9THV201014
- Price：Negotiable
- Clicks：319
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | EC:2.7.11.1, EC:3.6.1.-, RIO kinase 1, RIO1, RIOK1, Serine/threonine-protein kinase RIO1 |
| Immunogen | E. coli - derived recombinant Human RIOK1 (Thr180-Val479). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9BRS2 |
| Background | Serine/threonine-protein kinase RIO1 (RIOK1) is a ~65 kDa protein. Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor. The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. 1. Widmann, B. et al. (2012) Molecular biology of the cell 23, 22-35. PMID: 22072790 2. Guderian, G. et al. (2011) The Journal of biological chemistry 286, 1976-86. PMID: 21081503 |
| Note | For research use only |
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