Anti-Human CD242/ICAM4 Polyclonal Antibody
- Cat. No.：RB9THC421014
- Price：Negotiable
- Clicks：346
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | CD242, ICAM-4, ICAM4, Intercellular adhesion molecule 4, LW, LW blood group protein, Landsteiner-Wiener blood group glycoprotein |
| Immunogen | E. coli - derived recombinant Human CD242/ICAM4 (Met52-Trp234). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q14773 |
| Background | Intercellular adhesion molecule 4 (CD242/ICAM4) is a ~29 kDa protein. Functions as a receptor ligand for the monocyte/macrophage-specific ITGAX:ITGB2 integrin complex and mediates erythrophagocytosis. Receptor ligand of the platelet-specific ITGA2B:ITGB3 integrin complex involved in heterotypic cell-cell adhesion between erythrocytes and activated platelets. In vitro, is also a receptor ligand of multiple integrin receptors complexes such ITGAL:ITGB2, ITGAM:ITGB2, ITGA5:ITGB1, ITGA5:ITGB3 and ITGA5:ITGB5 integrin complexes. 1. Ihanus, E. et al. (2007) Blood 109, 802-10. PMID: 16985175 2. Hermand, P. et al. (2003) The Journal of biological chemistry 278, 4892-8. PMID: 12477717 3. Hermand, P. et al. (2004) European journal of biochemistry 271, 3729-40. PMID: 15355350 4. Hermand, P. et al. (2000) The Journal of biological chemistry 275, 26002-10. PMID: 10846180 5. Spring, FA. et al. (2001) Blood 98, 458-66. PMID: 11435317 |
| Note | For research use only |
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