Anti-Human GAR1 Polyclonal Antibody
- Cat. No.：RB9THD530014
- Price：Negotiable
- Clicks：191
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Rat, Human |
| Target | GAR1, H/ACA ribonucleoprotein complex subunit 1, NOLA1, Nucleolar protein family A member 1, snoRNP protein GAR1 |
| Immunogen | E. coli - derived recombinant Human GAR1 (Val71-Arg160). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9NY12 |
| Background | H/ACA ribonucleoprotein complex subunit 1 (GAR1) is a ~22 kDa protein. Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. |
| Note | For research use only |
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