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Anti-Human TBL1X Polyclonal Antibody

  • Cat. No.:RB9THF868014
  • Price:Negotiable
  • Clicks:266

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Human
TargetF-box-like/WD repeat-containing protein TBL1X, SMAP55, TBL1, TBL1X, Transducin beta-like protein 1X, Transducin-beta-like protein 1, X-linked
ImmunogenE. coli - derived recombinant Human TBL1X (Val218-Lys577).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberO60907
Background

F-box-like/WD repeat-containing protein TBL1X is a ~62 kDa protein. F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.

1. Perissi, V. et al. (2004) Cell 116, 511-26. PMID: 14980219
2. Oberoi, J. et al. (2011) Nature structural & molecular biology 18, 177-84. PMID: 21240272
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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