Anti-Human UGT8 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Mouse, Human, Rat
Target	2-hydroxyacylsphingosine 1-beta-galactosyltransferase, CGT, Ceramide UDP-galactosyltransferase, Cerebroside synthase, EC:2.4.1.47, UDP-galactose-ceramide galactosyltransferase, UGT4, UGT8
Immunogen	E. coli - derived recombinant Human UGT8 (Ala21-Gln471).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q16880
Background	2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) is a ~61 kDa protein. Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Galactosylates both hydroxy- and non-hydroxy fatty acid-containing ceramides and diglycerides. 1. Kapitonov, D. et al. (1997) Biochemical and biophysical research communications 232, 449-53. PMID: 9125199
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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