| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Human, Rat |
| Target | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase, CGT, Ceramide UDP-galactosyltransferase, Cerebroside synthase, EC:2.4.1.47, UDP-galactose-ceramide galactosyltransferase, UGT4, UGT8 |
| Immunogen | E. coli - derived recombinant Human UGT8 (Ala21-Gln471). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q16880 |
| Background | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) is a ~61 kDa protein. Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Galactosylates both hydroxy- and non-hydroxy fatty acid-containing ceramides and diglycerides. 1. Kapitonov, D. et al. (1997) Biochemical and biophysical research communications 232, 449-53. PMID: 9125199 |
| Note | For research use only |