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Anti-Human UGT8 Polyclonal Antibody

  • Cat. No.:RB9THD525014
  • Price:Negotiable
  • Clicks:464

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Human, Rat
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase, CGT, Ceramide UDP-galactosyltransferase, Cerebroside synthase, EC:2.4.1.47, UDP-galactose-ceramide galactosyltransferase, UGT4, UGT8
ImmunogenE. coli - derived recombinant Human UGT8 (Ala21-Gln471).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ16880
Background

2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) is a ~61 kDa protein. Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Galactosylates both hydroxy- and non-hydroxy fatty acid-containing ceramides and diglycerides.

1. Kapitonov, D. et al. (1997) Biochemical and biophysical research communications 232, 449-53. PMID: 9125199
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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