| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse, Rat |
| Target | ADCY2, ATP pyrophosphate-lyase 2, Adenylate cyclase type 2, Adenylate cyclase type II, Adenylyl cyclase 2, EC:4.6.1.1, KIAA1060 |
| Immunogen | E. coli - derived recombinant Human ADCY2 (Ala294-Thr525). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q08462 |
| Background | Adenylate cyclase type 2 (ADCY2) is a ~123 kDa protein. Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors. 1. Ding, Q. et al. (2004) Molecular pharmacology 66, 921-8. PMID: 15385642 |
| Note | For research use only |