| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | EC:6.3.4.21, FHA-HIT-interacting protein, FHIP, NAPRT, NAPRT1, NAPRTase, Nicotinate phosphoribosyltransferase, Nicotinate phosphoribosyltransferase domain-containing protein 1 |
| Immunogen | E. coli - derived recombinant Human NAPRT (Met1-Pro538). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q6XQN6 |
| Background | Nicotinate phosphoribosyltransferase (NAPRT) is a ~57 kDa protein. Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis. 1. Hara, N. et al. (2007) The Journal of biological chemistry 282, 24574-82. PMID: 17604275 2. Galassi, L. et al. (2012) Biochimie 94, 300-9. PMID: 21742010 3. Marletta, AS. et al. (2015) FEBS open bio 5, 419-28. PMID: 26042198 |
| Note | For research use only |