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Anti-Human ARL1 Polyclonal Antibody

  • Cat. No.:RB9THD512014
  • Price:Negotiable
  • Clicks:211

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityRat, Human, Mouse
TargetADP-ribosylation factor-like protein 1, ARL1
ImmunogenE. coli - derived recombinant Human ARL1 (Met1-Gln181).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP40616
Background

ADP-ribosylation factor-like protein 1 (ARL1) is a ~20 kDa protein. GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells.

1. Man, Z. et al. (2011) The Journal of biological chemistry 286, 11569-78. PMID: 21239483
2. Nakamura, K. et al. (2012) The Journal of biological chemistry 287, 25478-89. PMID: 22679020
3. Galindo, A. et al. (2016) Cell reports 16, 839-50. PMID: 27373159
4. Wang, R. et al. (2016) Journal of molecular cell biology 8, 459-461. PMID: 27436755
5. Hong, JX. et al. (1998) The Journal of biological chemistry 273, 15872-6. PMID: 9624189
6. Lu, L. et al. (2003) Molecular biology of the cell 14, 3767-81. PMID: 12972563
7. Gehart, H. et al. (2012) Developmental cell 23, 756-68. PMID: 22981988
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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