Anti-Human CDT1 Polyclonal Antibody
- Cat. No.：RB9THD509014
- Price：Negotiable
- Clicks：421
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | CDT1, DNA replication factor Cdt1, DUP, Double parked homolog |
| Immunogen | E. coli - derived recombinant Human CDT1 (Thr112-Ser386). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9H211 |
| Background | DNA replication factor Cdt1 is a ~60 kDa protein. Required for both DNA replication and mitosis. DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC). Required also for mitosis by promoting stable kinetochore-microtubule attachments. Potential oncogene. 1. Wohlschlegel, JA. et al. (2000) Science (New York, N.Y.) 290, 2309-12. PMID: 11125146 2. Sugimoto, N. et al. (2004) The Journal of biological chemistry 279, 19691-7. PMID: 14993212 3. Miotto, B. et al. (2011) Molecular cell 44, 62-71. PMID: 21856198 4. Varma, D. et al. (2012) Nature cell biology 14, 593-603. PMID: 22581055 5. Franz, A. et al. (2016) Nature communications 7, 10612. PMID: 26842564 6. Cook, JG. et al. (2004) The Journal of biological chemistry 279, 9625-33. PMID: 14672932 |
| Note | For research use only |
Related Products:
| Product Name | Clicks |
|---|---|
| NGAL单克隆抗体 | 7631 |
| 白细胞介素6（IL-6）单克隆抗体 | 7367 |
| 肝素结合蛋白单克隆抗体 | 6725 |
| CRP单克隆抗体 | 7536 |
| 猫胰脂肪酶单克隆抗体 | 7294 |
| 马SAA单克隆抗体 | 7380 |
| 犬腺病毒单克隆抗体 | 6892 |
| 犬轮状病毒单克隆抗体 | 6971 |
| 犬血红蛋白单克隆抗体 | 7808 |
| 犬胰脂肪酶单克隆抗体 | 6840 |
| 犬松弛素单克隆抗体 | 7111 |
| 犬冠状病毒单克隆抗体 | 7221 |
| 犬瘟病毒单克隆抗体 | 6862 |
| 犬细小病毒单克隆抗体 | 7178 |
| 猫瘟病毒单克隆抗体 | 7523 |
| 猫疱疹病毒单克隆抗体 | 7143 |
| 猫杯状病毒单克隆抗体 | 7559 |
| 猫SAA单克隆抗体 | 7224 |
| 犬CRP单克隆抗体 | 7748 |
| 犬、猫IgG单克隆抗体 | 7140 |