Anti-Human MIEF1 Polyclonal Antibody
- Cat. No.：RB9THD501014
- Price：Negotiable
- Clicks：261
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | AltMIEF1, AltMiD51, Alternative MIEF1 protein, MIEF1, MIEF1 microprotein, MIEF1-MP, Mitochondrial ribosome and complex I assembly factor AltMIEF1, alternative transcript upstream of MiD51 |
| Immunogen | E. coli - derived recombinant Human MIEF1 (Ala2-Ile70). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | L0R8F8 |
| Background | Mitochondrial ribosome and complex I assembly factor AltMIEF1 is a ~8 kDa protein. Assembly factor involved in the biogenesis of the mitochondrial-specific ribosomes (mitoribosomes). Specifically associates with intermediates of the mitochondrial ribosome large subunit (mt-LSU) and is required for proper ribosome assembly, possibly preventing premature association of the large and small ribosomal subunits. Thereby, indirectly regulates mitochondrial translation. It is also required for complete assembly of the mitochondrial respiratory chain complex I. May also function in DNM1L-mediated mitochondrial fission. 1. Brown, A. et al. (2017) Nature structural & molecular biology 24, 866-869. PMID: 28892042 2. Rathore, A. et al. (2018) Biochemistry 57, 5564-5575. PMID: 30215512 3. Dibley, MG. et al. (2020) Molecular & cellular proteomics : MCP 19, 65-77. PMID: 31666358 |
| Note | For research use only |
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